ABSTRACT
Abstract Introduction The use of 3D imaging in the medical field has proven to be a benefit to doctors when diagnosing patients. As for different medical applications, 3D visualization systems have advantages in terms of a better spatial understanding of anatomical structures, better performance of tasks that require high level of dexterity, increased learning performance, and improved communications with patients or between doctors. Methods In this technical report, we show how to employ a multi-view autostereoscopic system to provide 3D images without any special glasses or equipment, describing a new way to obtain 3D visualization using sets of 2D images instead of real volumetric data such as magnetic resonance imaging (MRI) or computed tomography (CT). We also propose an application of the images in neuroanatomy. Results We obtained three-dimensional images of anatomical parts for visualization without glasses with resolution of 336 × 210 pixels'. Conclusion The proposed method was able to generate three-dimensional high-resolution images and has great potential to be used in various areas such as anatomy and physiological studies.
ABSTRACT
The objective of the study was to research the distribution features of HLA-DRB1 alleles in Shandong Hans' population and explore the possibility of finding the cord blood donor of HLA-DR matched to perform the stem cell transplantation for more patients from larger region of China and even other areas in the world. The subjects of the study were drawn from 3 438 Shandong Hans donors in Shandong Umbilical Cord Blood Bank and were tested by PCR-SSP technique for HLA-DR low resolution typing. The result indicated that the most prevalent five alleles of HLA-DRB1 locus were DRB1 * 15 (0.1817), * 07 (0.1369), * 09 (0.1221), * 04 (0.1084) and * 12 (0.1038). The DR18 has the lowest gene frequency 0.0003, while DRB1 * 10, * 16 and * 01 showed lower gene frequencies (GF), which GF were 0.0151, 0.0262, and 0.0322 respectively. As compared the HLA-DRB1 GF of Shandong Hans with those of other Han Chinese and other ethnic populations, there were unique distributed features of DRB1 alleles among various races populations, and those among the studied population groups from various regions with the same race origin. The difference from various regions in the same race was less than that among different races. In conclusion, a patient of Han Chinese is easier to search a DR-matched cord blood donor in Shandong Umbilical Cord Blood Bank, especially from northern Hans. No DRB1 allele is unique to single racial group and majority of DRB1 low-resolution phenotypes are common to all studied groups. It is reasonable for some patients from other races including Caucasian and Japanese to receive a transplant of cord blood stem cell matched with HLA-DR in Shandong Umbilical Cord Blood Bank.